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> asdf: NPR, current events
cmac
post Sep 22 2008, 10:23 AM
Post #211





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travis barker is the man. i agree with everything jessica said.
anyone that can make this song even somewhat respectable is a god:
http://www.youtube.com/watch?v=RKQgDY0pZ68


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Mommy
post Sep 22 2008, 10:29 AM
Post #212


New son Donovan Charles Mummert born July 17, 2008


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QUOTE (cmac @ Sep 22 2008, 10:23 AM) *
travis barker is the man. i agree with everything jessica said.
anyone that can make this song even somewhat respectable is a god:
http://www.youtube.com/watch?v=RKQgDY0pZ68
THAT was FUCKING BAD ASS
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Spectatrix
post Sep 22 2008, 10:49 AM
Post #213





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Oh god, that made my ears bleed...


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QUOTE (pebkac @ Oct 14 2006, 03:15 PM) *
You and your logic.

QUOTE (Foamy)

http://xkcd.com/386/
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FORSAKENR320
post Sep 22 2008, 02:02 PM
Post #214


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QUOTE (cmac @ Sep 22 2008, 11:23 AM) *
travis barker is the man. i agree with everything jessica said.
anyone that can make this song even somewhat respectable is a god:
http://www.youtube.com/watch?v=RKQgDY0pZ68



your opinions are respected so little on these boards that your endorsement actualy hurts jessica's arguement instead of helping.


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QUOTE (Jessica @ May 7 2007, 01:15 PM) *
but yeehaw dammit. YEEHAW
QUOTE (Dogmeat @ Jun 26 2008, 07:51 PM) *
ok once upon a time I jacked myself off retarded.


Licking anuses, one kindergarten class at a time!!
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Mommy
post Sep 22 2008, 02:45 PM
Post #215


New son Donovan Charles Mummert born July 17, 2008


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QUOTE (FORSAKENR320 @ Sep 22 2008, 03:02 PM) *
your opinions are respected so little on these boards that your endorsement actualy hurts jessica's arguement instead of helping.
Maybe his music beliefs are better than his political beliefs. Well... scratch the maybe. The man at least knows his drummers.
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cmac
post Sep 22 2008, 03:27 PM
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music is obviously exactly the same thing as politics. i mean the comparisons are endless.
moron.


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FORSAKENR320
post Sep 22 2008, 06:30 PM
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QUOTE (cmac @ Sep 22 2008, 04:27 PM) *
music is obviously exactly the same thing as politics. i mean the comparisons are endless.
moron.


no, i just think that in general you're an absolute idiot


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QUOTE (Jessica @ May 7 2007, 01:15 PM) *
but yeehaw dammit. YEEHAW
QUOTE (Dogmeat @ Jun 26 2008, 07:51 PM) *
ok once upon a time I jacked myself off retarded.


Licking anuses, one kindergarten class at a time!!
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Psykopath
post Oct 3 2008, 02:10 AM
Post #218


Why so serious?


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Actually found this article kind of interesting:
http://news.yahoo.com/s/nm/20081002/sc_nm/us_obesity_brain

QUOTE
Calorie overload sends the brain haywire: study

By Maggie Fox, Health and Science Editor Thu Oct 2, 3:05 PM ET

WASHINGTON (Reuters) - Overeating makes the brain go haywire, prompting a cascade of damage that may cause diabetes, heart disease and other ills, U.S. researchers reported on Thursday.

Eating too much appears to activate a usually dormant immune system pathway in the brain, sending out immune cells to attack and destroy invaders that are not there, Dongsheng Cai of the University of Wisconsin-Madison and colleagues found.

The finding, reported in the journal Cell, could help explain why obesity causes so many different diseases. It might also offer a way to prevent obesity itself.

"This pathway is usually present but inactive in the brain," Cai said in a statement.

Obesity is a growing global problem, with 1.8 billion people estimated to be overweight or obese in 2007. Drugs marketed so far to fight obesity have only limited success and, often, severe side-effects.

Cai's team worked in mice, seeking to explain studies that have shown that obesity causes chronic inflammation throughout the body. This inflammation is found in a range of diseases related to obesity, including heart disease and diabetes.

They homed in on a compound known as IKKbeta/NK-kappaB.

Immune cells such as macrophages and leukocytes use it but Cai's team found it in the hypothalamus, a part of the brain linked with metabolism in mice and humans alike.

"The hypothalamus is the 'headquarters' for regulating energy," they wrote.

They found high levels of the compound there but it was normally inactive.

When they fed mice a high-fat diet, it became extremely active. And when it was active, the body ignored signals from leptin, a hormone that normally helps regulate appetite, and insulin, which helps convert food into energy.

Stimulating IKKbeta/NK-kappaB made the mice eat more, while suppressing it made them eat less.

Cai believes his team has discovered a master switch for the diseases caused by overeating.

"Hypothalamic IKKb/NF-kB could underlie the entire family of modern diseases induced by overnutrition and obesity," his team wrote.

Cai does not know why this compound would be in the brain and in the immune system but suspects it evolved long ago in primitive animals that do not have the same sophisticated immune system as modern animals, including mice and humans.

"Presumably it played some role to guide the immune defense," Cai said in a telephone interview. "In today's society, this pathway is mobilized by a different environmental challenge -- overnutrition."

"Knocking out" the gene using genetic engineering kept mice eating normally and prevented obesity. This cannot be done in people but Cai believes a drug, or even gene therapy, might work.

With gene therapy, a virus or other so-called vector is used to carry corrective DNA into the body, but the approach is still highly experimental.

(Editing by Julie Steenhuysen and John O'Callaghan)


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Psykopath
post Oct 3 2008, 11:59 PM
Post #219


Why so serious?


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OJ: Guilty on all charges.

Finally he'll be where he belongs- rotting in jail.


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Dogmeat
post Oct 4 2008, 08:38 AM
Post #220


DEATH TO ....something?


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B-b-b-b-b-b-but....!

Da black man be OPPESSED by da white man!
It not da black man fault da white man stole frum da black man!
Whyyyyyyyyyyyyyyyyyyyyyyy caint da black man get whut hiz? Whyyyyyyyyyyyyyyyyyyyyyyy?


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I r Ur Gawd!
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jonathan83
post Oct 4 2008, 09:41 AM
Post #221





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he's gonna spend the rest of his life behind bars.


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Psykopath
post Oct 7 2008, 02:26 PM
Post #222


Why so serious?


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http://news.yahoo.com/s/ap/20081007/ap_on_..._re/wall_street

Stocks keep falling...Dow is now at 9,447.


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Mommy
post Oct 7 2008, 07:10 PM
Post #223


New son Donovan Charles Mummert born July 17, 2008


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I went to radio shack today and the assistant manager was on the phone with somebody when I walked in. She gets off the phone, turns to a co-worker and says "Jo (inserted name because I forget the real one) lost $500 of his retirement." Her co-worker says "Wow, only $500... that's not bad." Assistant manager says, "Five hundred.... thousand."


Guess he won't be retiring anytime soon. That fucking sucks... Losing $500,000 of your retirement. My parents lost 20% of their retirement. I don't know how much that is, but that's still a lot to lose.
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Billy
post Oct 7 2008, 08:10 PM
Post #224


N 0 t h i n g


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McCain is doing pretty well this debate.


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QUOTE (jonathan83 @ Nov 16 2007, 09:22 PM) *
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Psykopath
post Oct 7 2008, 08:16 PM
Post #225


Why so serious?


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I'm actually disappointed in BOTH candidates...

I mean, they're both doing good in respect to typical debate structure and poise. But neither candidate is willing to go out of their comfort zone and be very firm with a stance or go strongly on the offensive.
I'm hoping that's mainly due to the format, but it was the same situation the last time they faced off. =/

This post has been edited by Psykopath: Oct 7 2008, 08:17 PM


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